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Police got called to an overcrowded presentation on “rejuvenation” technology (technologyreview.com)
32 points by robinhouston on June 18, 2023 | hide | past | favorite | 55 comments



Starship, AI and now anti-aging - It seems like 2023 is the year of sci-fi tropes. My pet theory is that Haim Eshed was right and there is a secret cabal of people in touch with post scarcity aliens with a cornucopia of fancy tech - but then they (in true sci-fi trope fashion) left the implementation to a committee of popular sci-fi novelists ...

All we need now is for boston dynamics to release their mech-warrior line...


I’ve thought about this a few times and I came to the conclusion that when you become a billionaire you become that alien to humanity. You are so far removed from average peoples needs you take on a fully alien mindset


Is it “when you become a billionaire” or is that mentality the reason you became one in the first place


“The future is here. It’s just not widely distributed yet”

- William Gibson


“Apple Vision Pro, only $3,500”


Quite fitting, as Gibson originally said that line after experiencing a VR demo

https://quoteinvestigator.com/2012/01/24/future-has-arrived/


On the flip side, overheating destroying crops and pushing heat past wet-bulb temperatures. Although mostly not in the rich West yet...


I´ll take your negative and raise a positive:

Substantial global progress has been made in reducing childhood mortality since 1990. The total number of under-5 deaths worldwide has declined from 12.8 million in 1990 to 5 million in 2021. Since 1990, the global under-5 mortality rate has dropped by 59%, from 93 deaths per 1000 live births in 1990 to 38 in 2021. Globally, the number of neonatal deaths also declined, from 5.2 million in 1990 to 2.3 million in 2021.

https://www.who.int/data/gho/data/themes/topics/topic-detail...


3499. Stop exaggerating /s


From. Do I bet without power bank.


Sure, but I look at it this way: if billionaires wan't to spend money on something, these technological long-shots aren't the worst they could do.

I'll take infinite amounts of these long-shots over a single WEF-esque attempt to reorganise society from the top down to institute a techno-fascist regime.


Dont worry, they don't spend any money on that cause it's basically already done.


Their robots can't even walk by the sea without being slowly destroyed by salt (and they are not really adapted to sand walking). So we are far.


Holy crap, MIT, I had to close out three popups to read the article. That’s with ad blockers turned on.

I’m surprised by how organizations lend their name to such terrible user experiences.


Not to defend MIT, but as I got zero with my blockers (uBo + uMatrix + FF tracking protection), maybe it’s time for an upgrade? ;) Might of course also be another reason.


Thanks. I’m on mobile safari so a bit of a pain to upgrade.

This is a rare experience for me, so I’m still calling out MIT for being at best thoughtless.


AdGuard is your best friend on iOS. FOSS software that blocks all ads. I read this article on my iPad with safari. No ads, no pop up.

https://apps.apple.com/us/app/adguard-adblock-privacy/id1047...


Check out the wipr plugin. It does a pretty good job of blocking popups and ads on ios safari.


Tested with Firefox, Privacy Badger, and NoScript - zero popups, zero ads.


MIT contributes tremendously to military technology. It's the primary purpose. I'd be concerned for that reputational and moral hazard such that the the UX challenges of a blog wouldn't even register.

Even Chomsky couldn't make it out clean and got sucked into state actor trouble.


MIT's entire reputation was _made_ by the military. It was a no name school before the contracts of WWII/The Cold War, e.g. the prominent radar lab https://en.m.wikipedia.org/wiki/MIT_Radiation_Laboratory


Four pop-ups for me.


I got another one from an add as well.


This article reads like something out of a Neal Stephenson novel. (See [0] for example.) The pop-up ads contribute to the on-brand, dystopian feel.

[0] https://en.m.wikipedia.org/wiki/Fall;_or,_Dodge_in_Hell


Sounds like a rich people trap. You can say anything if you don't show the results. Patents are also not a proof of anything remotely close to working. So for now they have... nothing?


Boomers have to spend their final portions wealth on incredible health care services to extend their life by a few months to years.


Is aging a disease?

I think this question is pivotal in how one analyzes the benefits and disadvantages in this space. The article links to a story that covers this a bit. I feel truly undecided on this question.


Technically, I think if something happens in 100% of cases that's the mainline and not an exception case that you can analyze/fix. So probably we cannot say it's a disease.

Now, in order to stop aging you will need to understand and stop all processes that lead to aging. everything we are doing today, in all domains, is trivial compared to understanding biology (even for simpler organisms). The complexity is just mindblowing (google: roche merabolic map poster). It would be probably easier (although this is still far far far out of reach) to create a new body and transfer the brain's content than to stop aging.

That should not stop us from trying to understand it though and there may be "low hanging fruits" that may add 1-2-10 years to life.

Another thing worth pondering is quality of life. If you could live the same amount of time without most of the decline that comes with old age who wouldn't want to do that?


If we collectively decide “yes” then maybe we can finally start devoting more resources to identifying and treating the underlying causes.

Let’s get rigorous and start separating snake oil from real science backed treatments.


It highly depends on the definition you use, gather them from wikipedia and a few dictionaries and you will see. Looking at it from different languages is also worth looking into. I see it as an unavoidable (so far and in my opinion for a long time) disposition to go through a process. As such I would not consider aging in general as a disease. But individual processes taking place in aging would be in my opinion, especially since they can happen at earlier age in some people. I am much more interested in providing better quality of life to people impacted by those than to everybody (the societal impact would be quite dramatic).


I don’t want to live forever, but I sure would be happy with 20 year old me’s ability to recover from physical exertion and injuries.


I'm nearly 40 and I still recover as fast as 20 year old me, if not faster.

My secret? Do not stop exerting.

(Exercise multiple times weekly)


My 20 yo self could do it without exerting, though.


Take care of your knees - the human knee is really a fuckup of evolution!


I discovered natural running in my twenties. It's a game- changer for your knees.


My thoughts exactly. If we live forever there is no need for (or resources to sustain) children. That would be bad in many ways.

I do totally agree that pouring “discretionary investments” into healthcare is perhaps more kind that other things (Mars fantasy).


>Is aging a disease?

The question is more relevant from a political/legal perspective but less so from a technical perspective. From a technical perspective the most important question is how do we go about fixing it.


This is a short story about thatquestion:

https://nickbostrom.com/fable/dragon


Any change in my body that is causing me discomfort is a disease.


So, stubbing your toe is a disease?

Anyway, the cure is a free, lifetime supply of fentanyl. Be careful what you wish for.


I wouldn't characterize growing pains as a disease.


Sunburn?


Car crash?


It’s a genetic disease in my main. The fact that it affects most animals is a matter of quantity, not quality.


> Altos, with an eye-popping $3 billion in startup funds, is among the best funded biomedical startups of all time, if not the richest of them all.

> The company has established three institutes, in Cambridge, UK, San Diego and in the San Francisco Bay area. Wolf Reik, leader of Altos’ Cambridge institute, also spoke during the Boston event and mentioned the “very beautiful building” Altos occupies there. He showed a photo of workers lined up in an atrium, who he referred to as “many happy people. Happy people in lab coats.”

> Unlike workers at universities, Altos researchers don’t have to spend time applying for grants. Altos pays its top staff salaries of one million dollars and more and doubles what junior scientists can earn.

At least we know where all that funding is going. Results still TBD.


A little off topic but since this mentions stem cells, I thought I’d ask: my wife is pregnant with our first child. The hospital has a (rather expensive) program where they will preserve the child’s stem cells from the placenta at birth. Their rep has been hounding me about it, but my doctor says not to bother.

Does anyone here have any experience with something like this? Is it something my child might benefit from, say, 15 years down the line?


> Their rep has been hounding me about it

In my opinion, the more aggressive the sales person, the higher margin they have. If it is something you want to do, negotiate on the price.


There are 2 questions here: 1/ can you afford it? Is paying the fee for the procedure for you like buying a meal at a fancy restaurant which you do without thinking too much about itor is it a lot of money? 2/ what are the odds of the kid developing a disease and the stem cells from the collected blood being usable for the said disease?

I would say go for it if financially this has virtually zero impact on you, but also be realistic about ever using it.


Just because you can afford something doesn't mean you should pay for it. Successful rich people are usually as diligent about a $1000 purchase as they are for $10M. Others with a "it's just a tiny bit of money, worst case it will go to waste, but maybe the snake oil actually works" attitude are prime targets for scammers and sleazy sales reps.

Doing your research is important no matter the price or product.


Three kids in three different hospitals (and two different states) in the US, and they all have this.

I don’t think it’s a hospital program it’s just an up-sell they get a kick-back on for selling to you.

It’s not a specific recommendation from that hospital, it’s the same as a car dealer upselling a third party insurance program.

As for value and utility, I think that’s covered here already, but I put it in the same bucket as cryogenics. Who knows where those stem cells go and how they’re maintained?

That said, my youngest is 10, so the state of science here might have changed since I last made the decision.


You’ve already got an answer from an expert working in the field who spent years studying and more years practicing.

Randos on the internet aren’t going to give you a better answer. If you want another perspective ask the rep to put you in touch with an MD who thinks it IS a good use of resources.


Would you pay a large amount for another speculative technology development (say Tesla auto pilot)?

Personally I would only do that if I know and care about the topic, in which case I would have an answer already.


I guesss Altos Labs are growth hacking with unsubtle PR.


Click for bait, stay for the science.


What happens if police doesn't disperse overcrowded masses: https://en.m.wikipedia.org/wiki/Seoul_Halloween_crowd_crush




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