As a general rule, the people on the short end of the stick are the people least capable of producing change. Worse, change that they bring about tends to be good from a strict, technical viewpoint but has huge negative side effects that go unnoticed or deliberately ignored until it becomes difficult to distinguish the resultant system as a better one.
Rants like this, and providing interviews to third parties, are actually one of the more positive things that he could bring to the table: it provides information to people who aren't aware and inspires motivation in people who aren't entangled.
I don't know, but I think Fred is in a prime position to disrupt bioinformatics. He knows all the flaws, he knows all the problems. If I were him, I'd have seized the opportunity and work on a hard problem.
Then again, I am in no position to judge what Fred should or should not do
Rants like this, and providing interviews to third parties, are actually one of the more positive things that he could bring to the table: it provides information to people who aren't aware and inspires motivation in people who aren't entangled.