We brought home a very anxious few month old rescue puppy and she wouldn't do anything but hide in her crate and she would shake whenever anybody came near her. After a couple of months of not really improving, the vet put her on Prozac and it worked amazingly. After a week or so she was making massive strides. About six months later, we weened her off the Prozac and she was comfortable enough with us that she didn't seem to need it any longer. She's now six, and still an anxious dog overall, but she loves us, is always happy to see us, and lives a pretty good life. Would she have come around even without the Prozac? Maybe, but I'm happy it seemed to have reduced her terror while she came to trust us.
