Although intermittent calorie restriction (CR) has been shown to lower IGF-1, this article shows that prolonged CR does not affect IGF-1 levels. However prolonged protein restriction, especially animal protein, _is_ shown to reduce IGF-1 levels.
Although intermittent calorie restriction (CR) has been shown to lower IGF-1, this article shows that prolonged CR does not affect IGF-1 levels. However prolonged protein restriction, especially animal protein, _is_ shown to reduce IGF-1 levels.