According to this article, it's a side effect of Ozempic itself. The article goes on to say that the newly discovered molecule can side-step the side-effect and metnioned that "obese mice treated with daily injections of BRP for 14 days lost an average of 3 grams—due almost entirely to fat loss..."
We don't know yet whether the muscle loss is caused by the drug itself or due to the weight loss, there are some studies but I haven't seen any conclusion yet one way or the other.
Anecdotally, a friend of mine was on a diet and exercise regime, then at some point he switched to Mounjaro to reduce cravings, while keeping the same diet and exercise regime (he's a data geek so he documented things pretty well), and his muscle gain maybe slowed a tiny bit, but didn't reverse on Mounjaro.
Also sample size of one, but with the weight loss from semaglutide, I've gotten back in the gym and I can now lift more weight than I ever have. It feels fantastic (both the weight loss and being strong)
I feel for you, friend. The safest way, however, is to make hunger your friend, and walk an hour or two a day. That may not work well with your work schedule, but you can override your body with your mind, unless your mind suffers because of our tech work's energy needs.
And, it takes me a day or two to get past a processed sugar addiction. After those couple of days, the body starts getting used to not having that "crack" energy source be a part of its desire-base.
Good luck, stavros, you can do it! And the sooner you start, the quicker you can get over the initial hump of resistence. Perhaps you can carrot yourself along by knowing that you WILL feel much, much better as the pounds start coming off and your body starts being able to walk a bit further or lift a few more weights. Fight the food inertia, my brother.
If you really want extra help, contact the Creator of the universe in the morning and evening, and ask It for help. If you do that with an intention to be able to better help others, you will find that the universe, itself, will become your ally.
We know that rapid weight loss causes muscle loss at a higher rate than slower weight loss in general.
GLP-1s might enhance this effect somewhat, but there is nothing definitive.
Adequate protein intake + resistance training can fully counteract it, however. I've even added significant lean body mass while losing fat while on GLP-1s.
You can't answer the Ozempic case without looking at research that compares people who rapidly lost weight with vs without the drug, and then looking at the %FFM difference between them.
It’s just absolutely not the case though. These drugs are now rife in the bodybuilding community, combined with a high protein diet and resistance training muscle will be retained. There is no mechanistic action to suggest that muscle loss would be caused by these drugs, quite the opposite actually.
Took me a while but finally found a consistent way to get it perfect.
I use long grain enriched white rice from Costco, wash the excess starch and dump the same amount of rice and water in the pot and let it cook on high for 4 minutes then 10 in low
Our school's headmaster advised me not to take computer science classes as they are "too difficult." It ended up being the class in which I got my best marks, I was the top student and made my living out of programming ever since.
> By the end of it, I hope my sons have a rich repository of childhood memories that will someday make them smile, laugh, and possibly even cringe.
Playing video games on the TV during the afternoons in our summer holidays are some of my favourite memories. As an introvert and nerd, it gave me time to decompress and practice some skills, while it gave my parents some time to nap and have kid-free time after a morning of playing on the beach in the sun.
Video games were also one of the things I could bond over and practice some comptetition with my dad and much-older sibling.
You can do both. My nephew is an absolute extrovert and socialises non-stop at school and afternoons in the park, but he looks forward to his 30 minutes to an hour on the PlayStation to decompress.
That's what you could report in your status meetings. I tried X, but it failed because Y. Then I installed Z and tried doing X again and then this happened.
As a team lead, I'd be more interested in hearing what you're thought process has been and what you've tried rather than just hearing about the final outcomes.
Very normal to feel a bit lost and out of your depth in the first few months or year at a new company - especially a larger one.
Your "carve out some work that needs to be done for myself" quote made me wonder though - what is your team setup? Do you have a project manager or anyone guiding you on what you need to work on? Or team members to ask questions?
Usually it's best to focus on the tasks that they expect you to do and provide them with regular feedback to keep them in the loop of your progress. If anyone else thought you need to be fired, you would've known by now.
It's a very untraditional project. No tickets, no sprints, no milestones, no retros, no ownership. It's a greenfield project and the bosses have decided to do things an untraditional way. Maybe it works? It's made it pretty difficult for me so far though so I wondered if I'm just a bad culture fit. I knew about it going in and was willing to try it.
Without knowing more I would say that if you want to stay at this organization start making friends throughout the org. It’s not typically very functional to not have bosses or ownership.
The structure and lack of direction of your group makes me worry your group may not be long for this world. You may be in a weird corner of the company.
My favourite lazy meal: bacon, creamed corn and cheddar pasta.
- Cook your favourite pasta and keep some of the pasta water.
- Cut bacon into pieces and cook in butter until browned.
- Add a can of creamed corn and some of the pasta water to the bacon.
- Add the cooked pasta and cheddar.
- Wait for the cheese to melt and enjoy!
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