Depends what you're using it for. If you're putting Debian on a server, go with netinst, deselect everything in tasksel during the install and then apt-get only what you need post installation.
That way you start with a very lean < ~700MB base install with no unnecessary garbage on your system to worry about.
That way you start with a very lean < ~700MB base install with no unnecessary garbage on your system to worry about.