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Trifexis is awesome and what I use for my active dog (and we have never had flea problems). The problem is that the pill smells very, very strongly of mold. I have to smash up the pill and mix it into peanut butter for my dog to even look at it. I also administer it outside and use gloves, because it will have your house smelling of mold for days. With a smaller dog (thus smaller dose/pill), you could force it down, but a 30+ lb dog will have too big of a pill and won't eat it normally for any reason.



Wow, It's amazing how different my experience with trifexis is. My dog eats them like they are a treat(wags her tail, chews them completely, etc). I've never really noticed the mold smell.


Does your dog throw up often when taking Trifexis? I was considering making the switch, but my parents dogs both have had a really hard time with it. Eventually they (my parents) gave up on Trifexis and went back to topical stuff because the vomiting was so bad.

To that end, I wouldn't mind maybe an accompanying table to the OP's medical list that maybe listed the negative side effects of some of these treatments. Might be a bit too much to ask though.


No, I haven't seen any vomiting. I was worried about that since I was breaking up the pill (and it smells awful) but my vet said it was fine since it is supposed to be chewable. I always serve it right after a full meal (usually the morning).


That's very surprising to hear. We have the 50+ lb dose, and I've never noticed a smell. My dog eats it like a treat without any coercion or disguising.


Really? I have never noticed this. I just put it in a piece of cheese and they eat it right up. Maybe I have no sense of smell.




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