I'm using a lot of them in production right now, thanks to transpilers. Unfortunately not everything can work without the aid of a run-time, which is how Traceur works. At the moment i'm limiting myself to the features that don't require such a run-time.
Then why not use something like https://6to5.org/ ? Most syntax features can be transpiled without a runtime (generators being an exception) and everything else can simply use polyfills.