Well this is a "hacker" forum, whom's origins are in software. Secondly, is it that hard to mentally substitute in your field of choice? e.g. "And if you can't work in the lab, and you can't get brilliant researchers to like and respect you, you probably shouldn't be an entreprenur"
Either way the quote is stupid. Had he said "...shouldn't start a software company" I'd be in full agreement. Despite what some people seem to implicitly assume the word "entrepreneur" isn't intrinsically tied to the software field. Saying if you suck at X you shouldn't be an entrepreneur doesn't make sense unless X is "being an entrepreneur".