It's also worth noting that ABP is an absolute pig, on either Firefox or Chrome. I found that memory consumption and machine churn significantly dropped when I simply removed it and lived with ads. I've done no empirical measures on this, but am convinced that the cure is worse than the disease.
Try uBlock, it is much faster than ABP and uses way less resources. Or do it the good old fashion way and use a HOSTS file with the added advantage that ads will be blocked on your entire computer and not just your browser.
I was actually completely unaware that Youtube had ads for a long, long time. I'm not sure I could move to a solution where I would be forced to watch them.
True, which is why I tried to be agnostic on the actual means of adblocking in my op. Regardless, it requires a level of openness on Apple's part that I'm being slightly delusional about wanting.
I'm using HTTP Switchboard which uses much less memory has offers a lot more control over what to block and what to allow through, but it does take a bit more configuration than ABP.
I'm getting really close to switching back to AdBlock for Safari (the one based on an old fork). It did a decent job my machines feel much older with ABP. I can see rendering delays on large pages.