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Yes, there are many (potential) problems caused by the homogeneous nature of research mice. It's an under-considered variable in a lot of research, and, from my knowledge, hasn't really been studied until recently.


I never before heard that this was a big issue; could you please tell what those problems are?


Anecdotally, tests for skin-contact carcinogens can be skewed because the lab mice are prone to develop skin cancers anyway.




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