Could you say more about your approach to print? I'm reasonably far along with a manuscript, and now I'm trying to figure out what to do with it. LeanPub seemed nice and easy, but they don't do print.
Start with the eBook and see how that goes: they're really cheap to produce. If it's going decently, reinvest some of the profits into making a print on demand book. Print and eBooks are very different, so what you invest in one won't translate to the other.
Aaron Shepard's books give a pretty good overview of how to publish on amazon.
Createspace is pretty easy to use. If you already have a pdf you sell online, you just have to format it for print, and put a cover on it. I found a designer on elance to help me with both.
Last time I looked LeanPub had an option to produce a print-ready PDF that you could then throw at something like Lulu. Info is somewhere in the author FAQ.
(Note: not done it myself - so don't know how well it works.)