If you're interested in using d3, check out dc.js ... http://nickqizhu.github.io/dc.js/ ... it's d3 with crossfilter.js added. Really useful for linking interactive charts together - filter on one applies the filter to all. And it's damn fast.
No, not a good idea due to performance limitations. d3 is very powerful framework but on most mobile devices you can't do anything that complex if it's animated (try the animated demos on a phone).
On the other hand if you're doing something less complex like charting, choosing a domain specific framework like highcharts.js can offer much higher frame rates.
This problem is much worse on iOS when using a browser like Chrome, or using Safari inside of an app. That's because Apple disables many JS optimizations when not using Safari or when using a browser window inside an app.
I'd like to use this opportunity to vent my frustrations using cubism.js. I love d3 and I love the idea of cubism. But doing a real-time cubism vis with custom data sources was a painful task. Not sure if it would be less painful than doing real-time horizon charts or sparklines myself.
