You can do that, but even in exactly the same market, two different companies (or contract firms, in my case) may want diametrically opposite changes to your resume (or CV, in your case). Here in the DC area, I was told to play down my business ownership and that the amount of money I was asking was "unrealistic" (and did I want to maybe talk about something 20-30K lower?) within a coupla weeks of being hired at more than the "unrealistic" salary by someplace I'd sent the older version of my resume. It's incredibly variable.