I only used it for a few minutes, but I installed it on my sister's netbook and she uses it exclusively. From what I saw, all applications looked exactly the same, save for the window manager chrome. Lubuntu is closer to Windows with a Start-like menu and the applications there, so if you're more familiar with Windows, you will probably find it easier.
I haven't delved deep into it, so I couldn't tell you how easily you can find the settings or whatnot, or if there are issues that aren't in another window manager. Given that you can install it with just an "apt-get install lubuntu", though, it'll probably be faster if you tried it yourself!
