If you insist on using stimulants such as amphetamine,
learn about how to reduce tolerance with things such as
NMDA antagonists and take things to prevent neurotoxicity.
He should also get on with trying Noopept - it's one of
the best nootropics of recent times.
>The increase of cytosolic dopamine appears to trigger neurotoxicity, as dopamine readily auto-oxidizes, so that amphetamine or methamphetamine's increase in cytosolic dopamine can lead to oxidative stress in the cytosol that in turn promotes autophagy-related degradation of dopamine axons and dendrites
NMDA antagonists such as magnesium (as mentioned by rms), zinc, DXM, MK-801, Memantine and Ketamine can reduce/prevent tolerance as well as nerotoxicity.
