The karma barrier to entry is a good first pass. Though, if someone wanted to get their resume on the site they could find ways around the karma. (Automated upvoting of a story/comment that they made for example.)
There should be a way for the top 100[0] people to flag the profile as spam which would strip them of the right to post a resume.
There should be a way for the top 100[0] people to flag the profile as spam which would strip them of the right to post a resume.