Clearly you missed the part about name-calling. Anyways, that's a false dichotomy since you can be a third option: someone that's skeptical of messing with an important energy consumption pathway in the human body.
The baseline of "energy consumption pathways in the human body" now is to be severely messed up.
Humans did not evolve for an environment where food is overly abundant and physical activity is optional. For almost the entire evolutionary history of humans, this just wasn't the case. But it is what humans are having to deal with today.
Now, take a look at the "metabolic syndrome" and its prevalence. Clearly, there's a lot of room for improvement.
By all accounts, this generation of GLP-1 agonists has found a meaningful way to improve on that baseline. The benefits are broad and the side effects are manageable. This isn't "surprising" as much as it is "long overdue".