pry-rescue is a modernization thereof (banisterfiend helped me build it).
The only technical difference is that pry-rescue can catch exceptions raised at the C level (like NoMethodError, or ZeroDivisionError); but pry-rescue also has a much easier-to-learn API/UI. (Particularly, by only supporting catching unhandled exceptions, pry-rescue can avoid the need to predicate on which exceptions should be handled).
The only technical difference is that pry-rescue can catch exceptions raised at the C level (like NoMethodError, or ZeroDivisionError); but pry-rescue also has a much easier-to-learn API/UI. (Particularly, by only supporting catching unhandled exceptions, pry-rescue can avoid the need to predicate on which exceptions should be handled).