> If you eat 2000 kCals of lettuce, your body is going to do very, very different things to eating 2000 kCals of potato fries, including how it stores or consumes energy in that moment.
I don't really think so. The only meaningful difference regarding the content of macronutrients is right at the start: you would have to eat about 20kg of lettuce to get there, which would overload your digestive system several times over.
If you hypothetically somehow managed to bypass this small issue, the main difference would be low fat content of lettuce compared to the fries. Bud the body can adapt to that.
I don't really think so. The only meaningful difference regarding the content of macronutrients is right at the start: you would have to eat about 20kg of lettuce to get there, which would overload your digestive system several times over.
If you hypothetically somehow managed to bypass this small issue, the main difference would be low fat content of lettuce compared to the fries. Bud the body can adapt to that.