When I realized how powerful TRAMP was, I don't think I ever used screen/tmux again. I'm sure there are uses, mind. Just TRAMP fully hit all of my needs.
It really is magical, isn’t it? And although I rarely need to use it, I love the multihop setups where you can ssh to this system, then ssh again to this other, then mount an SMB filesystem using these credentials, and start editing.