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Absolutely, it is possible.

I’m not sure about the depression, but it sounds plausible, depending on the experience. That’s out of my expertise, though.

For a concrete example, phantom limb pain can be a form of affective emotional pain, with a huge asterisk in that, it’s more complicated that than only resulting from #2. Too complex to get into in this forum. Here’s reading if you’re interested:

https://pmc.ncbi.nlm.nih.gov/articles/PMC6051014/#:~:text=.n...



In the case of phantom pains, one can point out "where on my body, what type (hot? cold? chemical?), and how intense is the noxious stimulus?". That's the sensory-discriminative component. It is just that limb is missing. One explanation is that brain stores the map of various limbs, etc.




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