Hacker Newsnew | past | comments | ask | show | jobs | submitlogin

GLP-1 is a class of drugs (or molecules). The first known GLP-1 was pretty much just a synthesized version of a naturally occurring compound from the Gila Monster’s venom.

Semaglutide is like a 2nd generation GLP-1 and there are 3rd generation ones in development right now




Semaglutide and co are "GLP-1 receptor agonists" that behave in a similar way to the naturally occurring hormone GLP-1.

We can't give people GLP-1 itself because it breaks down really fast and you'd have to provide it continuously, so we use ones that effect the body the same way over a long period of time.


Yeah, halflife of GLP-1 is about 5 minutes.


Ah ah, I see what your original comment meant now! I parsed that completely differently :)

Yes you’re right.


Gila Monster is a pretty cool name for a lizard




Consider applying for YC's Fall 2025 batch! Applications are open till Aug 4

Guidelines | FAQ | Lists | API | Security | Legal | Apply to YC | Contact

Search: