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> We have pretty good evidence that increasing consumption of saturated fat increases risk of cardiovascular disease

We have evidence to suspect this [1]. We are not yet able to predict in which people it’s the case moreso (or at all) than others.

[1] https://pubmed.ncbi.nlm.nih.gov/34649831/






This just sounds like a semantic disagreement. I believe the evidence base presented in the paper is a pretty fair representation of the field, and justifies the authors’ statement:

> the totality of the evidence supports the recommendation to limit SFA intake to <10% TDE for the general healthy population

I would call this pretty good evidence. Perhaps you wouldn’t but, as I say, that’s probably just a semantic disagreement.


> would call this pretty good evidence

Sure, I would too. I wouldn't call it strong evidence one way or another. The error bars suggest there is too much in-population variance to come up with useful general guidelines. (Frying an egg in a tablespoon of lard every day wouldn't constitute 10% TDE on a 2,000-calorie diet, for example.)


> The error bars suggest there is too much in-population variance to come up with useful general guidelines.

I’m not sure I’d agree there. What’s the argument for that?




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