Hacker News new | past | comments | ask | show | jobs | submit login

> Iodine deficiency today is the leading cause of preventable mental retardation in the world. It’s estimated that nearly one-third of the world’s population has a diet with too little iodine in it, and the problem isn’t limited to developing countries — perhaps one-fifth of those cases are in Europe (pdf), where iodized salt is still not the norm.

https://web.archive.org/web/20200820212020/https://www.who.i...

> The Recommended Dietary Allowance (RDA) for iodine is between 220 micrograms (mcg) and 290 mcg in pregnancy, and 290 mcg when breastfeeding. [1]

Iodine affects the thyroid which produces hormones that regulate how the brain develops in the womb. If these T3/T4 hormones aren't strong enough, brain cells don't get into the right places.

Apparently Iodine intake needs to be 50% higher than the normal healthy level during pregnancy (and higher during breast feeding). Taking prenatal vitamins now in case I get pregnant.

[1] https://www.ncbi.nlm.nih.gov/books/NBK582771/

[2] https://www.phind.com/search?cache=l34zoyrwfc8ocb3vcodcsc46

So when neurons form in the brain, they are born in a nursery and then migrate to their final destination. Here is a movie showing this, https://www.youtube.com/watch?v=OMYHx7dRe8g

Mapping Postnatal Neuronal Migration: A Late Path to Neurodevelopmental Disorders https://www.youtube.com/watch?v=E4FZiv-rtTU

Neurogenesis in the mammalian brain https://www.youtube.com/watch?v=B2RINOAeONw






This was both a new topic to me and a remarkably succinct (and well-cited) comment. Did you happen to do this research independently or do you reference a more comprehensive source?

I love doing research so I tried to answer the question for myself, "why does iodine deficiency cause cognitive impairment"? I have no background here.

Then I discovered that brain cells walk around during brain formation. MindBlown!




Consider applying for YC's Spring batch! Applications are open till Feb 11.

Guidelines | FAQ | Lists | API | Security | Legal | Apply to YC | Contact

Search: