It just looks better. Text specifically will look much crispier in a 4K 27" monitor at 150% scaling than a 1440p 27" monitor at 100% scale, despite both having the same working space.
Yeah.. Exacly this. I recently started to look for monitor, and dug up site with DPI etc. That high DPI monitors annoys me a lot, its actually very hard to get anything w/ Pixel Size larger than 300um. Smaller pixel put a lot of strain on my old eyes... And upscaling really suxx.. unless you do 200% with means you need to buy expensive gear like 150um pixel size.. and upscale x2...
Going from 2k / 27" to 4k / 27" screens severely reduced my eye strain after a long day of code-staring. Both were IPS panels so I can only attribute it to the incredibly sharp text rendering.