SSRIs have all kinds of horrible effects that are seldom acknowledged, that's why it's exciting that ketamine is getting popular for treating things like depression, anxiety, and OCD. Besides how you feel a few hours after treatment most people notice close to zero side effects. For some people its anti-depressive effects can be quite long lasting. It's considered a second line treatment for depression, but from what I've seen it needs to be moved to the front of the line.