On: In SSRI withdrawal, brain zaps go from overlooked symptom to center stage (2023)

[thescriptkiddie]

I've gotten them from taking SNRIs, so I wonder if norepinephrine is involved somehow, or maybe SNRIs are not actually that selective.

[_moof → thescriptkiddie]

If you're talking about Effexor - famous for wicked brain zaps after only one missed dose - this could have more to do with its very short half life.

[jrflowers → thescriptkiddie]

The S in SNRI stands for Serotonin, not Selective.

[jamedjo → jrflowers]

Today I Relearned: Selective Serotonin Reuptake Inhibitor (SSRI) != Serotonin Norepinephrine Reuptake Inhibitor (SNRI) != Selective Norepinephrine Reuptake inhibitor (sNRI)

[partomniscient → jamedjo]

There are also SDRI and SDNRI. D -> Dopamine.

[fzzzy → jrflowers]

Wow, I did not know that. Good to know.

[p1anecrazy → thescriptkiddie]

The only time I got them was getting off a high dose of Strattera (atomoxetine), the rare non-stimulant ADHD medication, cold turkey.

[larve → thescriptkiddie]

got them after weaning of SNRIs, for about 1-2 years I had random brain zaps. Not that big of a deal per se, but definitely annoying.