Guile probably has the best Emacs integration through Geiser. While you don't really need it and you can just follow along with a terminal REPL, using something like Geiser helps keeping the experience smooth.
MIT/GNU Scheme comes with its own editor, edwin, which is a terminal-only Emacs-like. I don't know how much it complies with the various RnRSes, but I do believe it's good enough to work for the Little series.
Gauche is R7RS-small (and I believe -large up to Tangerine) compliant so it should just work. It also has fairly good Geiser support and comes with an enormous standard library, 'batteries included' as they say, though its performance is a bit lower than some of the other implementations.
Cyclone is R7RS-small compliant so it should work. It seems fairly fast and it has a package manager, but because it's fairly new I don't know how well it works with Geiser.
Loko is R6RS compliant so it should work. I believe the documentation says that it should work with Geiser using the Chez module, but I may be mistaken.
Gerbil is R7RS-small compliant (and I believe -large through Red, maybe through Tangerine?) so it should work. I believe it's also quite performant, though I haven't used it.
Kawa is R7RS-small compliant if I'm not mistaken. If so it should work for the Little series. It also has a Geiser module.
And then there are a few implementations of which I'm not entirely sure which version of the spec they comply with and how well they're supported by various editors (though I think SLIME has Scheme support, although that may only be for MIT/GNU Scheme): Gambit (I think R5RS? Gerbil is built on top of it), Bigloo (I think R6RS?), Larceny, Chibi Scheme, Biwa Scheme, S7, and IronScheme. For any of those, as long as they support post R4RS macros (so using `define-syntax' and `syntax-rules' instead of `defmacro)' they should work for the Little series without any adjustments. If they're still using `defmacro' then you'd need to translate the macro definitions from Reasoned (and later?), which isn't that hard... but if you're gonna do that you may want to read On Lisp after Seasoned.
MIT/GNU Scheme comes with its own editor, edwin, which is a terminal-only Emacs-like. I don't know how much it complies with the various RnRSes, but I do believe it's good enough to work for the Little series.
Gauche is R7RS-small (and I believe -large up to Tangerine) compliant so it should just work. It also has fairly good Geiser support and comes with an enormous standard library, 'batteries included' as they say, though its performance is a bit lower than some of the other implementations.
Cyclone is R7RS-small compliant so it should work. It seems fairly fast and it has a package manager, but because it's fairly new I don't know how well it works with Geiser.
Loko is R6RS compliant so it should work. I believe the documentation says that it should work with Geiser using the Chez module, but I may be mistaken.
Gerbil is R7RS-small compliant (and I believe -large through Red, maybe through Tangerine?) so it should work. I believe it's also quite performant, though I haven't used it.
Kawa is R7RS-small compliant if I'm not mistaken. If so it should work for the Little series. It also has a Geiser module.
And then there are a few implementations of which I'm not entirely sure which version of the spec they comply with and how well they're supported by various editors (though I think SLIME has Scheme support, although that may only be for MIT/GNU Scheme): Gambit (I think R5RS? Gerbil is built on top of it), Bigloo (I think R6RS?), Larceny, Chibi Scheme, Biwa Scheme, S7, and IronScheme. For any of those, as long as they support post R4RS macros (so using `define-syntax' and `syntax-rules' instead of `defmacro)' they should work for the Little series without any adjustments. If they're still using `defmacro' then you'd need to translate the macro definitions from Reasoned (and later?), which isn't that hard... but if you're gonna do that you may want to read On Lisp after Seasoned.