Answer to this will totally depend on the scenario. Figure out what your RPO and RTO is on each thing and build out backups and failovers accordingly. If this is anything but a personal lab, you will likely need both db level backups (ie get this db back to this time) and vm level (the datacenter went down, good thing we have all our vms backed up offsite). Veeam comes to mind and one tool I’ve seen work well. Backup services built into cloud providers is what I use for most things these days
