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For anyone who would like to know more about designing proteins with a certain function, target, or structure in mind, the term to search for is "rational design."

https://en.m.wikipedia.org/wiki/Rational_design




Thank you for this, terms of art are the silent gatekeepers...


As an aside, learning the precise terms for concepts in fields in which I'm a layperson (or simply have some cobwebs to shake loose)--and then exploring those terms more--is something that I've found LLMs extraordinarily useful for.


Also "off target effects".




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