We're already engineering ecosystems in a thoughtless way. I find it hard to believe that messing with mosquito genetics is going to make the world significantly more risky than it already is for humanity.
Ecosystems are complex systems that can't be perfectly modeled. So its possible that just the right perturbation could cause outsized harm and that we wouldn't be able to tell ahead of time what that might be.
Just because we've 'gotten away' with messing with ecosystems so far does not mean that we continue to do so indefinitely.
It's like saying its hard to believe that a single additional straw could break a camel's back when so many have been piled on before without issue. You're right until, suddenly, you're wrong.
> It's like saying its hard to believe that a single additional straw could break a camel's back when so many have been piled on before without issue. You're right until, suddenly, you're wrong.
And in this case, the example is updated that even any single straw could break / could have broken the camel's back.