On: Dual action antibiotic could make bacterial resistance nearly impossible

[zabzonk]

> 100 million times

do you know how many bacteria, all mutating and swapping genes, there are out there?

also, dual therapy, particularly for TB has been used for years, but TB is still with us.

[gcanyon → zabzonk]

But drug resistance is already really hard to develop. As you say, there are an almost unfathomable number of -- let's say staph -- bacteria running around, infecting millions of people per year, and still it's taken most of a century to develop MRSA. 100 million times might make MRSA v2 take millennia to arrive.

[aziaziazi → gcanyon]

As we see an exponential grow or the human population, shouldn’t your estimation for v2 be pondered compared to v1 development?

[klyrs → aziaziazi]

Actually, the rate of population increase peaked in the 1960s. The growth once seen as exponential is beginning to look like an s-curve, if you pay attention to the derivative.

[jajko → aziaziazi]

I dont think you understand the word exponential.

[aziaziazi → jajko]

I think I do but I made the common mistake of mismatching exponential with accelerated growth.

My interrogation hold : aren’t bacteria infections quantity (and therefore duplication and mutation) influenced by the growing number of host?

[John23832 → zabzonk]

> also, dual therapy, particularly for TB has been used for years, but TB is still with us

1/4 people carry TB in the world. Most asymptomatic.

TB been with humans as long as humans have been around, and it will be with humans as long as we're here.

Multidrug Resistent TB is a thing though.