Somebody upthread pointed out that it installs a root CA and forces all of your HTTPS connections to use it. I verified that he's correct - I'm on Hacker News right now with an SSL connection that's verified by "ZScaler Root CA", not Digicert.
ZScaler has various deployment layouts. Instead of the client side TLS endpoint, you can also opt for the "route all web traffic to ZScaler cloud network" which office admins love because less stuff to install on the clients. The wonderful side effect is that some of these ZScaler IPs are banned from reddit, Twitter, etc, effectively banning half the company.