Are there serious issues with wxwidgets? When I was looking for this sort of things it was unglamorous, but had decent bindings with several languages and looked decent enough. I agree with your assessment of the other alternatives.
If I go with C++, I'll take QT, which has lot more extensive controls library and in fact allows me to be more productive than wxw.
Unfortunately, the main productivity limiter is C++ and that's something I really want to avoid. I've been writing C++ professionally for about 8 years so I think I can make such statements.
