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> However, in about 10% of the instances in which AlphaFold2 was “very confident” about its prediction (a score of at least 90 out of 100 on the confidence scale)

I wonder what that confidence score means... If it is 90% probability, then we'd expect it to be wrong 10% of the time




If you're actually interesting, you can read about the scoring here:

https://www.ebi.ac.uk/training/online/courses/alphafold/inpu...

Long short, it's a lot more complex than just % probability the atoms have proper Cartesian coordinates.




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