This appears to sacrifice more horizontal space, I don’t see this coming to desktops in its current incarnation as motherboards are already super cramped and replacing 4 ram slots for one doesn’t seem like a trade off most users are willing to make.
Maybe it's thin enough that you could squeeze it onto the back side of the motherboard? It would be annoying to build that way, but there's plenty of space there.
It may be annoying to assemble the machine with memory modules on the back of the board, but as far as manufacturing the board this connector is ideal for putting memory on the back: it's just exposed pads on the motherboard, no soldered connector. So it's even simpler to manufacture than something like putting a M.2 slot on the back.
> replacing 4 ram slots for one doesn’t seem like a trade off most users are willing to make.
Having four slots on consumer motherboards is already nearly vestigial in the DDR5 era: two slots is already enough to hit 96GB (128GB later this year), and filling all four slots with dual-rank modules comes with severe speed penalties. Buying a single module rather than a kit with a matched pair is an improvement for consumers. The main sacrifice with LPCAMM2 is losing the ability to reach a quad-rank configuration. But the current limit of 64GB with LPCAMM2 for a mainstream processor with a 128-bit memory bus is definitely sufficient for most consumer desktops, including basically any gaming desktop.