> One who thinks that the important question is: "Which quantities are random?" is then in this situation. For the first researcher, n was a fixed constant, r was a random variable with a certain sampling distribution. For the second researcher, r/n was a fixed constant (approximately), and n was the random variable, with a very different sampling distribution. Orthodox practice will then analyze the two experiments in different ways, and will in general draw different conclusions about the efficacy of the treatment from them.
But so then the data _are_ different between the two experiments, because they were observing different random variables -- so why is it concerning if they arrive at different conclusions? In fact, the _fact that the 2nd experiment finished_ is also an observation on its own (e.g. if the treatment was in fact a dangerous poison, perhaps it would have been infeasible for the 2nd researcher to reach their stopping criteria).
