I probably saw this first on HN, but here is is anyway:
The 404 page for the Catholic diocese of Pittsburgh features the Catholic patron saint of lost items:
They changed it, but my all time favorite is probably the one Bloomberg once had. It had a gif of a guy in a suit in front of a computer falling apart (the guy!).
Okay, I overplayed it a bit.
But, honestly, I mean it: it is a great example of what happens when people care about their cause. Words fail me to praise this enough.