I certainly will try it, once we get AMD drivers to a happier place. Unfortunately, Nvidia's proprietary drivers are not ideal for community debugging, and Nouveau is a little rough on arm64.
The PCIe implementation on the 5 is supposedly more complete/less broken than on the CM4, but so far the only person crazy/inspired enough to test hasn't gotten back to this card with their Pi 5 setup.
Previous-gen video cards were often connected to risers that only provided 1x, and lots of "normal" systems (with a bit of expansion) don't have enough PCI Express lanes to give 16 lanes to any one device.
RPi5 exposes 1 lane on the PCIe connector. It routes 4 lanes to the 2040 chip that provides much of the board's I/O.
IMO 1 lane is better than none. I love the CM4 because it exposes 1 PCIe lane and that can support a NVME SSD making it the first Pi that supports what I consider to be a decent storage interface.
I know it's a terrible idea, and I can't afford the mortgage, but can I?