I'm aware of malvertising, and have also spent time in front line tech support. Why does this make the web "unsafe and unusable" without an ad blocker?
From the Wikipedia page you linked, it's clear all vectors for automatic intrusion and traditional pop-up fakery are well blocked. Even malicious spoof sites are being blocked at record speeds on the browser level.
In addition, ads are not the only (or even the primary) method of malware delivery. At best if you think an ad-blocker makes you "safe", this is a false sense of security.
If you apply common sense, there's no scenario where normal web browsing is "unsafe".