Perhaps! That’s just the auto formatted text from an Amazon share link on iOS - no referral code in the link!
His patents were exhaustively written and documented in medical textbook style (rather than legal robot style) further detailing the variety of uses of citrulline:
The essence is arginine is crucial in the production of NO, which serves many functions of the body but it’s also a powerful vasoprotector. Sickle cell is popularly thought to cause anemia due to the cell shape not carrying enough oxygen, but in fact it’s due to the shape irritating the epithelial cells lining blood vessels, particularly small vessels and capillaries. This redirects the use of arginine in the body to repairing and protecting the blood vessels in the body.
Citrulline is an intermediate non essential amino acid found in high concentration in watermelon seeds (hence the name). It survives the gut, unlike direct arginine ingestion, and converts readily to arginine in the kidneys (my grandfather was an expert in kidney function and pioneered kidney transplants in the 1950’s and 1969’s, his interest in sickle came late in his career in the 1990’s).
He was also an expert in heart disease, and as a young man was a tenured professor of medicine at University of Kentucky, chair of cardiovascular research, and an endowed member of the Kentucky Heart Association. He left Kentucky to found the first regional hospital and medical school in eastern North Carolina, ECU, where he was the director for many years. He was a terror of grad students, never accepted outside grant money for any of his research, never worked with drug companies, and led the bioethical research boards at his medical school for most of his career. He earned the nickname Dr House for his remarkable ability to diagnose obscure diseases and conditions along with novel treatments using his encyclopedic knowledge of biochemistry and disease, as well as his often obnoxious personality. The university forced him to retire because he brought no funding and had an entire floor for his lab when he was in his late 70’s, so he tore out his garage and built a laboratory in its place where he spent the rest of his years self publishing new research.
His patents were exhaustively written and documented in medical textbook style (rather than legal robot style) further detailing the variety of uses of citrulline:
https://patents.google.com/patent/US5874471A/en
The essence is arginine is crucial in the production of NO, which serves many functions of the body but it’s also a powerful vasoprotector. Sickle cell is popularly thought to cause anemia due to the cell shape not carrying enough oxygen, but in fact it’s due to the shape irritating the epithelial cells lining blood vessels, particularly small vessels and capillaries. This redirects the use of arginine in the body to repairing and protecting the blood vessels in the body.
Citrulline is an intermediate non essential amino acid found in high concentration in watermelon seeds (hence the name). It survives the gut, unlike direct arginine ingestion, and converts readily to arginine in the kidneys (my grandfather was an expert in kidney function and pioneered kidney transplants in the 1950’s and 1969’s, his interest in sickle came late in his career in the 1990’s).
He was also an expert in heart disease, and as a young man was a tenured professor of medicine at University of Kentucky, chair of cardiovascular research, and an endowed member of the Kentucky Heart Association. He left Kentucky to found the first regional hospital and medical school in eastern North Carolina, ECU, where he was the director for many years. He was a terror of grad students, never accepted outside grant money for any of his research, never worked with drug companies, and led the bioethical research boards at his medical school for most of his career. He earned the nickname Dr House for his remarkable ability to diagnose obscure diseases and conditions along with novel treatments using his encyclopedic knowledge of biochemistry and disease, as well as his often obnoxious personality. The university forced him to retire because he brought no funding and had an entire floor for his lab when he was in his late 70’s, so he tore out his garage and built a laboratory in its place where he spent the rest of his years self publishing new research.
https://www.legacy.com/us/obituaries/reflector/name/william-...