It’s been a while since I’ve been deep in the field, but the basics are you’ve got a first order action and a second order action.
T cells in this instance are directly cytotoxic. They find the ligand they bind to, and they begin lysis of the cell to kill it.
Meanwhile the intent of the mRNA vaccines that so many of us received over the last several years was to get B cells pumping out immunoglobulins which would soak up virus, reducing severity/duration of illness and allowing time for the bodies other defences to swing into action.
They’re not the same mechanisms of action (or at least they don’t rely on the same levers at the same strengths). Like everything in the human body, it’s a stochastic process so bits of everything are happening at once
Regardless of the intent of the vaccines, the evidence is fairly clear that they induce a CD8+ response, and the manufacturers seem fairly proud of this fact. Here a paper I found in a few seconds of searching:
T cells in this instance are directly cytotoxic. They find the ligand they bind to, and they begin lysis of the cell to kill it.
Meanwhile the intent of the mRNA vaccines that so many of us received over the last several years was to get B cells pumping out immunoglobulins which would soak up virus, reducing severity/duration of illness and allowing time for the bodies other defences to swing into action.
They’re not the same mechanisms of action (or at least they don’t rely on the same levers at the same strengths). Like everything in the human body, it’s a stochastic process so bits of everything are happening at once