Hacker News new | past | comments | ask | show | jobs | submit login

Note that the article discusses research studies and not clinical trials for drug or device approval.

These research studies are important (look at how many were conducted on COVID-19 over the last few years) but are typically not held to a particularly high standard, as with most science. Which doesn’t excuse bad data or poor statistics (the latter supposedly supposed to be picked up in peer review).




Hmm, I read the article as explicitly calling out "clinical trials" (as referenced in the title and abstract) and it makes no reference research studies. I don't understand the distinction between "research studies" and "clinical trials", surely all research studies where an RCT is performed with real patients and real drugs is a clinical trial?


I meant “trials for research studies” as opposed to “trials for drug or device approval.”

The amount of record keeping and oversight of a drug approval trial is enormous (and as a consequence insanely expensive) — data handling, having disjoint groups at each stage handling and analyzing data, etc and detailed records of every manufacturing step — think ISO9000 on steroids.

Nobody would bother to go to that effort for a scientific exploration, nor should they. So the bar is much lower.

I am making no excuse for shoddy science! But it is quite unlikely for a licensed drug.




Guidelines | FAQ | Lists | API | Security | Legal | Apply to YC | Contact

Search: