If it changes your odds from "1 in 100" to "1.6 in 100", you might have better things to spend your time worrying about. Absolute risk is important to keep in mind, not just relative risk.
Depends on things like other risk factors, though. And like you say, if you can isolate ten genes that each have a similar effect, then you're getting somewhere.
Depends on things like other risk factors, though. And like you say, if you can isolate ten genes that each have a similar effect, then you're getting somewhere.