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I found Kurzgesagt has a very good ELI5 on how cancer grows in the body: https://www.youtube.com/watch?v=zFhYJRqz_xk

I have lung cancer, stage 4.

My cancer has a mutation that is uncommon in lung cancers (< 2%), but common in breast cancers (> 25%). All of the treatments for my mutation are breast cancer treatments. It has been alternately not too bad and hellish getting insurance to agree to give me medications that could be saving my life. That plus a previous steroid-treated pneumonitis disqualifies me from about 90% of clinical trials, so the tip-of-the-spear treatments (CRISPR-T, CRISPR-NK) are unavailable to me.

So yes, lots of advancements are being made...in common cancers. Uncommon cancers, we have to wait and take the older stuff, or stuff that's just been approved.

And even through all of that, it's a crap shoot as to whether it will work or not. I took 2 conjugates, in the same class of medication - each had a slightly different chemo med. One worked fabulously, about halved the size of my main tumor. The other did nothing, and ended up giving me neuropathy in my feet (it can be numbness, but in my case it felt like my feet were on fire, 24/7. I am on a medication now to fix that, and my feet feel totally normal). Fun fact - the neuropathy chances for that med were stated as 0%. I guess someone rounded down from 0.1%, because I got it.




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