It's also interesting that essentially none of the native animals in Africa are domesticatable -- I think donkeys are the one thing we managed to domesticate there, most everything else was brought back from other continents.
Animals you'd think would be basically like other species we've domesticated, like zebras or gnus, take a strong "fuck you" attitude towards people and have resisted modern efforts to domesticate them.
So NA megafauna had no problems with wolves but people come along and it’s game over. Still not buying this. Why did horses die out but not bison or deer? How did mammoth go extinct while elephants didn’t when elephants faced more technologically advanced humans over a longer time period? Just doesn’t add up.