I feel like the strongest issue I have with Jira, and the one that most often trips me up, is that so many features and settings are global, and aren't the minimal set. For a sufficiently large org, you need a high degree of rigor around things like Labels and Epic naming, or you end up with labels of "production" "prod" "Prod" and "PROD" and no one knows which one to use.
It only gets worse when you're working with addons - half of the UI of any ticket is things I have to go hide because one team integrated Figma with Jira and now it shows up on every project and ticket.
The issue is Jira's permission management also seems terrible in the exact way that makes it hard to create that sort of role without making that person also responsible for a myriad of banal options that everyone needs turned on.
It only gets worse when you're working with addons - half of the UI of any ticket is things I have to go hide because one team integrated Figma with Jira and now it shows up on every project and ticket.