Obesity, longevity, and hormonal research are actually aligned on many points. Nutritional science, which is primarily built upon epidemiology, has caused a lot of confusion as seen in the article, and this is the reason that the quote exists. However, other sciences do use mechanisms of action.
So, it's not hopeless; any emergent system that is as flexible as the human body will be really complex, with balances, counterbalances, and even counter-counterbalances. It's built to survive almost any climate and adapt to changes in climate within a short time span.
Be aware that bodybuilders have been using different metabolic states since the time of Vince Gironda, around the 1960s.
The human body is made for many ranges, contexts, and different diets. So searching the best diet won't yield much.
So, it's not hopeless; any emergent system that is as flexible as the human body will be really complex, with balances, counterbalances, and even counter-counterbalances. It's built to survive almost any climate and adapt to changes in climate within a short time span.
Be aware that bodybuilders have been using different metabolic states since the time of Vince Gironda, around the 1960s. The human body is made for many ranges, contexts, and different diets. So searching the best diet won't yield much.