Along the same lines, people here are underestimating the scale of lab grown meat production. IIRC it'd have to be something like 40,000 factories costing close to $2T to build, and even then it would take decades to build them all. And the meat would be very expensive.
A lake of shit overflowing and poisoning the water table won't make the skies foggy. Granted, I am talking about rural things, that 26 story building probably has its own unique issues.
I think your underestimating the scale of animal agriculture.